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34 HuangZ.HuangL.WangC.ZhuS.QiX.ChenY.et al (2020a)

This was due to its ability to bind directly to the GLS1 promoter region, thereby promoting GLS1 expression [59]

In terms of secondary outcomes, the ALC group was also more likely to have had an improvement in cancer-related fatigue (31% vs

236 Interestingly, mice receiving young AD-MSCs exhibited significantly greater bone regeneration than those receiving aged AD-MSCs did, suggesting that the aging process diminishes the therapeutic potential of AD-MSCs in osteoporosis treatment

Theoretical advantages include reduced toxicity, enhanced cytotoxicity due to the ability to deliver higher concentrations of drugs that would be toxic if administered systemically, and the synergistic benefit of combined tumor kill from the antibody and the payload

[DOI] [PMC free article] [PubMed] [Google Scholar] 215.Pavel K., Damulin I