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Clinical Nutrition ESPEN 2023, 54, 412420

142 Additionally, mucin 20 (MUC20), a member of the mucin family encoded by human genes, represses CDKN2A expression by suppressing IGF-1R lactylation, triggering MET inactivation and cuproptosis to hinder proteasome inhibitor resistance in multiple myeloma cells

Lipo C is a compounded medication , not FDA-approved

Since renal medullary cells, whose role is to concentrate urine, are constantly exposed to extremely high levels of sodium chloride and urea, the accumulation of betaine in renal medullary cells helps balance the hypertonicity in interstitial fluid (Kempson et al., 2014)