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1998 Mar;12(3):225-41

Ascorbic acid is one of the most comprehensively studied antioxidants and is present in the majority of plant cell types, organelles, and apoplasts (Gill and Tuteja, 2010

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This review indicates that ferroptosis of retinal cells is involved in the progression of age-related/inherited macular degeneration, blue light-induced retinal degeneration, glaucoma, diabetic retinopathy, and retinal damage caused by retinal ischemia-reperfusion via multiple molecular mechanisms

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation