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The Hepatocyte Differentiation Basal Medium was composed of DMEM/F12, 10% KnockOut Serum Replacement (Thermo Fisher Scientific, Inc.), 1X NEAA, 1X PEST and 1X GlutaMAX Supplement (Thermo Fisher Scientific, Inc.)

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Gastrointestinal Symptoms : nausea, vomiting, diarrhea, constipation, abdominal pain, reflux, heartburn, and impaired motility Secretomotor Symptoms : difficulty sweating, tearing, and other fluid production (dry eyes, dry mouth, difficulty swallowing, dry skin)

Brit J Dermatol 142, 931936 (2000)

Distinct metabolomic signatures are associated with longevity in humans

Notably, members of the defensin family such as HNP1, hBD2, hBD3, and hBD4 have been reported to induce keratinocyte proliferation and migration, which can then secrete hBDs, promoting cellular barrier reconstruction and accelerating wound healing