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It is "metabolically expensive." It burns through energy faster than the average brain because it is hyper-sensitive to sensory input (light, sound, smell, barometric pressure)
The glycocalyx as a permeability barrier: basic science and clinical evidence

Incidence and prevalence of autoimmune liver diseases [Norweigan]
G-actin sequestration Primary function, essential for motility of fibroblasts, keratinocytes, endothelial cells and cardiomyocytes

doi: 10.1097/01.anes.0000267512.08619.bd
The comprehensive storage guide addresses these points in greater detail with specific recommendations for various peptide types
