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10.1007/s00268-012-1663-4 [DOI] [PMC free article] [PubMed] [Google Scholar] Vukojevic J., Siroglavic M., Kasnik K., Kralj T., Stancic D., Kokot A., et al

Nature 2018;562, 578-582, doi:10.1038/s41586-018-0543-y

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Missed doses complicate timing further

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We simulated the effect of joint CLP257 and L838,417 administrations under the assumption each drugs works on a distinct effector namely KCC2 activity for CLP257 and g inh for L838,417