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With increased aging, dogs exhibit AD-like neuropathology in brain including elevated levels of A42 (of the same amino acid sequence as that in humans), amyloid plaque formation, and hyperphosphorylated Tau protein (187)

Schoenmaker L, Witzigmann D, Kulkarni JA, Verbeke R, Kersten G, Jiskoot W, Crommelin DJA

F., Altman, D

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Am J Kidney Dis 2001 Nov