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Work in the subsequent three decades, driven substantially by Bernard Horecker at Cornell University, but with important contributions by other leading biochemists including Arthur Kornberg, Terry Wood, Frank Dickens, Fritz Lipmann, Severo Ochoa, Hans Klenow and others, yielded a draft version of the pathway that was presented in 1955 (Gunsalus, Horecker & Wood, 1955)

Both fat and water soluble, it is readily absorbed from the gut and crosses cellular and blood-brain membrane barriers [22, 53]

On non-exercise days, participants took their supplement in the morning with breakfast

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