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Nevertheless, neurons can detoxify H 2 O 2 , but apparently this capacity is more greater in astrocytes for which they play a putative role in the modulation of the neurotoxic effects of H 2 O 2 [45, 46, 52]

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Nakata R

Redox Signal 99 KimJ

Our subsequent studies in human endothelial cells showed that the homocysteine metabolite, S-adenosylhomocysteine, a potent inhibitor of many methyltransferases, decreased tRNA Sec methylation to suppress GPx1 expression and activity [69]

Lancet Oncol 13 (9): 906-15, 2012
