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Fumarate itself can covalently modify cysteines, and numerous protein targets of this posttranslational modification have been identified (43)

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Thus, the vitamin is considered to be the major lipid-soluble antioxidant in most species (9, 10)

It also plays a vital role in the body's natural detoxification pathways, helping to process and eliminate unwanted compounds
doi: 10.2147/ijn.S60270 [DOI] [PMC free article] [PubMed] [Google Scholar] 97.Xu B, Li S, Shi R, Liu H

This is less common but still a valid pathway
