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Current Medicinal Chemistry , 12(10), 11611208

541,542 Alterations in T-cell behavior result in heightened proinflammatory TH1 and TH17 responses, reduced immune monitoring affecting the elimination of infected or cancerous cells, diminished self-tolerance contributing to autoimmune conditions, and weakened natural defenses, ultimately fostering widespread inflammation

Loren Walensky, a professor of pediatrics at Harvard Medical School and a physician at Dana-Farber Cancer Institute, is also a senior author of the study, which appears in the Proceedings of the National Academy of Sciences the week of Jan
