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Although a higher lipophilicity should lead to an enhanced cellular uptake, as Pt(IV) complexes (unlike Pt(II) complexes) enter cells solely by passive diffusion, a lack of correlation between log P values and cellular Pt levels is not unprecedented 31,32

A short synthetic analog of an adrenocorticotropic hormone fragment, studied in Russian clinical literature for attention, stress resilience, and cognitive performance

63 GrekC

PMID: 27279982

These amino acids are bound together by covalent peptide bonds

This phenomenon is thought to be due to the inability of cells to restore normal GSH levels or to increased production of reactive oxygen species (ROS), which can damage macromolecules fundamental to cell survival before being deactivated by antioxidant defenses