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575 Similarly, the loss of mitochondrial complex I leads to a decrease in the ratio of NAD + /NADH and can inhibit the activity of Sirt3, thereby enhancing the protein acetylation and mPTP sensitivity

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Reduces the Symptoms of Parkinsons Disease Parkinsons disease is a well-known neurodegenerative disease with symptoms like motor function loss and cognitive decline, and the second most common neurodegenerative disease in the world

doi: 10.3389/frsfm.2025.1681598 Received 07 August 2025 Revised 13 November 2025 Accepted 17 November 2025 Published 12 January 2026 Volume 5 - 2025 Edited by Jay X

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