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Glutamine uptake via ASCT2 is sodium-dependent, meaning the transport is coupled to the movement of sodium ions into the cell, which helps drive the uptake of glutamine against its concentration gradient

[DOI] [PMC free article] [PubMed] [Google Scholar] 1176.Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G

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However, THC metabolites and other prominent phytocannabinoids such as cannabidiol (CBD) also contribute to the complex pharmacology of cannabis

Furthermore, the western blot shows that FXR antagonism by indomethacin induces the phosphorylation of STAT3 (signal transducer and activator of transcription 3), promotes the activation of caspase9 and finally causes DILI
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