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Unlike earlier compounds that affected multiple methyltransferases, 5-amino-1MQ demonstrates remarkable specificity for NNMT without inhibiting related SAM-dependent enzymes or components of the NAD+ salvage pathway

GLP-related metabolic frameworks( Product Specifications Compound: 5-Amino-1MQ Strength: 5mg per vial Form: Lyophilized powder Purity: Research-grade (see COA) Storage: Refrigerated conditions recommended Intended Use: Laboratory Research Use Only Certificate of Analysis (COA) Each batch of 5-Amino-1MQ 5mg research peptide is verified for purity and identity

This presentation provides a 5mg vial configuration suitable for experimental modeling, signaling pathway analysis, and laboratory research applications

This selectivity, combined with its ability to efficiently cross cellular membranes, makes it an invaluable research tool for dissecting the specific contributions of NNMT to metabolic regulation

Nature Chemical Biology 9(5):300-306

Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies