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However, for nebulized antibiotics the interpretation of the antibiogram should take into consideration that, through this form of delivery, antibiotic achieves much higher concentrations in the bronchial mucosa overcoming the mechanisms of resistance.77 The persistence of bacteria despite aggressive treatment is thought to be due to several factors such as poor penetration of antibiotics into purulent airway secretions, native or acquired antibiotic resistance and production of biofilms by the bacteria that may render antibiotics ineffective or interfere with host defences

New Insights into Nanomedicines for Oral Delivery of Glucagon-like Peptide-1 Analogs

The region-specific pattern of glutathione loss may also help guide future neuroimaging studies and more effective targeted therapies

Buckley AJ, Tan GD, Gruszka-Goh M, Scanlon PH, Ansari I, Suliman SGI

Chaudhary P., Janmeda P., Docea A

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