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Conflict of interest statement The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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Vitam Horm 100:165230

3 Cell (2017) in vivo resultsIn aged and progeroid mice, FOXO4-DRI reduced senescent-cell burden and restored fur density, renal function and fitness

however, at the same time temperature lowers the pKa of the acidic side chains in the C terminus thus facilitating the opposite effect of keeping fibrillation at bay

Huang Q, Su H, Qi B et al (2021) A SIRT1 activator, ginsenoside Rc, promotes energy metabolism in cardiomyocytes and neurons