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Only a subset of participants aged 55 and older showed a modest benefit approximately a 1 percentage point reduction in HbA1c (from 8.6% to 7.7%) and a slight increase in fasting insulin

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Menalled LB, Kudwa AE, Miller S, Fitzpatrick J, Watson-Johnson J, Keating N, et al

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CD38 is involved in multiple cell transmembrane signal transductions, including T cell activation, differentiation, and proliferation, B cell production and differentiation, as well as the induction of calcium ion release [4, 5]