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Reduced butyrate levels in CFS/ME patients may contribute to increased gut permeability (leaky gut), allowing microbial products like LPS to enter the circulation and trigger systemic immune activation (Wang J.-H

Similarly, Dengue infection also leads to ROS accumulation, resulting from the degradation of Nrf2 by a viral protein (NS2B3), leading to increased viral replication and inflammatory or apoptotic gene expression 35

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The emergence of novel coronavirus disease (COVID-19) in Bangladesh: present status, challenges, and future management