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S., Norwitz, N

Semaglutide: Begin at 0.25mg subcutaneously weekly, increasing to 0.5mg at week 4, then to 1mg at week 8, with potential escalation to 2.5mg for weight management

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CPT1 (CPT1A) deficiency is an extremely rare, autosomal recessively inherited disorder, with only some 60 cases worldwide reported so far

Lancet Psychiatry , 2021 , 8 (2), 130-140

In the largest observational study of 101 adult patients nave to diet therapy who subsequently started the MAD, 39% had 50% seizure reduction and 22% became seizure free following 3 months of treatment (23)