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Description
Its high lipophilicity allows easy crossing of biological membranes, including the BBB, resulting in accumulation in the CNS [89]

, Senthil S., Narayanan S., and Badhwar A

Sci Rep 9 , 6333 (2019)

Nicol M, Ferro Desideri L, Vagge A, Traverso CE (2021) Faricimab: an investigational agent targeting the Tie-2/angiopoietin pathway and VEGF-A for the treatment of retinal diseases

Excessive iron ions can activate the p38-MAPK pathway and block the PI3K/AKT and JAK/STAT3 signaling pathways, thereby inducing death in MC3T3-E1 cells [149]
It prevents chemically-induced changes in lab models of Parkinson's disease and exerts significant neuroprotection
