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10.3390/biomedicines12061350 [DOI] [PMC free article] [PubMed] [Google Scholar] 24.Karussis D, Petrou P, Kassis I (2013) Clinical experience with stem cells and other cell therapies in neurological diseases

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Abstract Diminished growth factor signaling improves longevity in laboratory models, while a reduction in the somatotropic axis is favorably linked to human aging and longevity

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Quercetin can inhibit oxidative damage induced by oxidized LDLoxldl in endothelial cells by activating SIRT1 and regulating AMPK signaling (Hung et al., 2015), and can also regulate the expression of various chromatin modifiers in a dose-dependent manner, such as reducing the activity of DNMT and HDACs and down-regulating global DNA methylation levels (Kedhari Sundaram et al., 2019)