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Description
Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle

Virol J
The accumulation of DPP9 leads to the overactivation of NRF2 and its transcriptional target SLC7A11, which inhibits ferroptosis and induces the resistance of ccRCC cells to sorafenib (142)

Furthermore, enhanced production of -KG causes other critical effects, such as stimulation of the signaling pathways that support cell growth

2015;1:S964

Resveratrol protects mouse embryonic stem cells from ionizing radiation by accelerating recovery from DNA Strand breakage
