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Muscle relaxants like baclofen and tizanidine are employed to manage muscle spasms and spasticity in conditions such as MS or spinal cord injuries 189 , 190

Angiogenesis and blood vessel formation

Neural upregulation Neuroendocrine pathways, such as the sympathetic nervous system and the hypothalamus-pituitary-adrenal (HPA) axis, oversee the bodys inflammatory responses

Cigarette smoke can disrupt neutrophil function by enhancing these two pathways, contributing to the pathological progression of COPD (87, 88)

Setting expectations appropriately based on individual circumstances helps maintain adherence through the time needed for full benefit

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