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2.2 Abnormal amino acid antioxidant system System Xc , GSH, and GPX4 constitute a critical signaling axis in the regulation of intracellular lipid peroxidation and ferroptosis (Yu et al., 2025)

Trials 25, 385

Artificial intelligence and big data for personalized preventive healthcare: predicting health risks and enhancing patient adherence

Hepatozoon sp infection in bobcats

High levels of HO inactivate protective peptides like ACTH and -MSH, while decreasing enzyme activities like methionine sulfoxide reductase, consequently intensifying oxidative damage and accelerating melanocyte death 46

This decrease can be accelerated by poor lifestyle choices like an unhealthy diet, inactivity, or toxin exposure contributing to increased oxidative stress linked with age-related conditions