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Also, CBD reduced oxidative stress levels and prevented the decrease in dopamine levels (17)

Additional strategies, such as synthetic or stabilized specialized pro-resolving mediators, neuroprotective anti-inflammatory agents, and dietary or microbiome-based interventions that shift mediator balance toward resolution, may offer complementary options for patients who continue to exhibit low-grade inflammation despite adequate systemic control (66)

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Apoptosis of retinal cells occurs early in DR, with accelerated capillary cell death detectable even before the appearance of histopathological changes (81)

How oxidized low-density lipoprotein activates inflammatory responses

The role of drug transporters at the bloodbrain barrier