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PH patients usually progress to CKD rapidly: mean age at ESRD onset in PH1 patients is 2427 years

Leathem, A., Simone, M., Dennis, J

The production of AMPs from IECs is also modulated by intestinal microbes

& Pittet, M

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The mechanisms involved in GABA release were first investigated in beta cell lines, where GABA secretion was shown to be dependent on the presence of extracellular Ca 2+ [105], suggesting that GABA is released in response to an increase in cytosolic Ca 2+ levels