glutathione detox pathways IV Liver Explained Schematic diagram of the glutathione-based
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Rather, the relationship between p62 and NRF2 is much more complex

Stewart NJ, Sato T, Takeda N, Hirata H, Matsumoto S

10.1016/j.kint.2017.09.033 106 LiuF.WangY.ZhouX.LiuM.JinS.ShanA.et al (2021)

What it does is significantly accelerate and enhance the bodys own repair mechanisms, ones that exist and function without it but that operate more slowly and less efficiently in its absence

This suggests that precise local application might not be entirely necessary to achieve the desired outcome

Clin Nutr Suppl 2012, 7: 265
