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Our knowledge of the properties of albumin reveals a molecule with multiple treatment options in patients with cirrhosis, from the compensated then decompensated phases to multiple organ dysfunction

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ES2 results in apoptosis and a survival advantage in different melanoma mouse models and senolysis in aged mice To determine if ES2 could eliminate a developing cancer that is induced into senescence, we utilized two different mouse models: (i) a transgenic mouse model of melanoma, and (ii) an orthotopic xenograft mouse model

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The genetic variations among CC genotypes resulting from this polymorphism witness an impaired binding of ECSOD to the extracellular matrix, leading to lower tissue levels of the enzyme in comparison to individuals carrying CG and GG genotypes (Srheim et al., 2010)