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REDEFINE 2 Trial Protocol

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Begin with the lowest effective dose Observe response over 37 days Increase only if results plateau and no side effects are present In peptide therapy, conservative titration with consistent monitoring tends to yield better outcomes and fewer side effects than aggressive front-loading. Milekic, T

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Escalation: Step the dose up every few weeks e.g

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With further study, this peptide may help treat periodontal disease

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however, at 4 weeks of age, these mice demonstrated increased ATP levels in their skeletal muscle 262

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