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Animal models of multiple sclerosis: the good, the bad and the bottom line

Physiological Reviews

Grogginess if the dosage is too high

The FDA's accelerated approval pathway and the EMA's adaptive pathways program have further intensified Phase II DCT adoption by incentivizing sponsors to generate early efficacy signals from broader, more representative patient populations an objective directly facilitated by hybrid and decentralized enrollment models that extend geographic reach without proportional site network expansion

No immediate access to a medical professional if a complication arises

Shahrokhi M, Ghaeli P, Arya P, Shakiba A, Noormandi A, Soleimani M, et al