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This represents meaningful human evidence for wound healing applications, supporting the tissue repair mechanisms observed in animal models
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At the cellular level, BPC-157 has been linked to activation of repair-associated signaling pathways, including Egr-1 with its regulator NAB2, and FAKpaxillin signaling, which are potentially involved in cell adhesion and migration
Activation of NF-B appears from these studies to be critically regulated by intracellular thiol redox status
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