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This gives it a half-life long enough to support once-weekly dosing, a major practical advantage over earlier amylin-based therapies like pramlintide, which required multiple daily injections

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As a naturally occurring chemical, GHRH derives from the hypothalamus, an area of the brain that coordinates the bodily system (i.e., the endocrine system) responsible for controlling just about every important function needed for internal stability growth, energy, metabolism, and reproduction, as well as responses to injury, stress, and mood.4 5 True to its name, GHRH causes the pituitary gland to release growth hormone