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24 The accumulation of ROS in cells directly damages biomolecules such as nucleic acids, membrane lipids, structural proteins, and enzymes, leading to cellular dysfunction or death
Armstrong 2014
222 359385 (Academic Press, London, 1993)

Neuroinflammation is triggered by the activation of microglia and astrocytes, which release proinflammatory factors that exacerbate neuronal damage [214]

These differences can be explained, at least in part, by the different probes used for the assessment (106)

Folic acid inhibits homocysteine-induced superoxide anion production and nuclear factor kappa B activation in macrophages