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Selected Publications Fu K, Bonora G, Pellegrini M, "Interactions between core histone marks and DNA methyltransferases predict DNA methylation patterns observed in human cells and tissues", Epigenetics (2019)

Overall, data showed that systemic infection by ACLSV did not produce any visible symptoms or membrane damage in leaves (i.e., no changes in lipid peroxidation), while antioxidant defenses increased, including GST

Furthermore, positive correlations were observed between CYP2E1 promoter methylation and both iNOS promoter methylation and urinary levels of SPMA

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Beyond these direct antioxidant actions, HTY has reported to influence cellular redox homeostasis by modulating signaling pathways associated with antioxidant defense, most notably those linked nuclear factor erythroid 2related factor 2 (Nrf2), resulting in increased expression of phase II detoxification enzymes such as heme oxygenase-1 (HO-1), superoxide dismutase (SOD), catalase (CAT), and NAD(P)H quinone dehydrogenase 1 (NQO1) [6]

Despite substantial success in treating liquid tumors, identifying appropriate tumor antigen targets (and overcoming exhaustion) for solid cancer-targeting CAR T cells remains challenging 115