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Severe and persistent side effects

You have some wiggle room, but if you fall off your schedule for too long, those signs of fatigue will inevitably return, and they almost always arrive on the scene before any other symptom does

Taking upward of 3 grams a day is generally considered safe by the FDA

Research indicates that cigarette smokers, diabetics, alcohol drinkers, and individuals with digestive problems are also prone to being B12 deficient

Grubisic MM, Strbe S, Barisic I, Balenovic D, Stambolija V, Lozic M, Ostojic SB, Oreskovic I, Zizek H, Brcic K, Coric L, Staresinic M, Blagaic V, Oreskovic LB, Halle ZB, Matek D, Soldo D, Grizelj B, Blagaic AB, Skrtic A, Seiwerth S, Sikiric P

J Physiol 236(2):303326 Costa M, Brookes SJ, Steele PA, Gibbins I, Burcher E, Kandiah CJ (1996) Neurochemical classification of myenteric neurons in the guinea-pig ileum