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The mechanisms underlying mitochondria release and uptake by recipient cells are still unclear

Front Pharmacol 2022;13:797499

Its true that the cells that were overexpressing NOX4 and that were in oxidative stress before the oxygen deprivation ultimately experienced more oxidative stress than normal cells but those cells would have cut off the flow of glucose in much quicker and averted disaster

A status report

the second type of FIN, such as DPI7, directly inhibits the activity of GPX4 and produces lipid ROS (Yang et al., 2014)
