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Three parameters mainly determine the specific and effective Cre-loxP recombination in vivo : (1) the dose and duration of TAM that determine the activity of the potent metabolites 4-OH-TAM and END, (2) the level of Cre ERT2 expression and (3) the chromatin structure and epigenetic status of the floxed alleles
Cavallucci, V
B12 absorption requires a protein called intrinsic factor , produced in the stomach
These findings provide strong evidence that circulating IGF-1 modulates NVC responses in the murine brain
It influences mood, emotions, and mental processes
