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GTP effects on GLUD1 are not localized solely to the subunit to which it is binding and that the antenna plays an important role in communicating this inhibition to other subunits
Effect of NAC as an Attenuator on A-Peptide Aggregation The greater the aggregation of A peptides, the greater the presence of alterations in neuronal plasticity, neuroinflammation, and cholinergic and dendritic pathways, among other consequences

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Rheumatology 58 , 927 (2018)
Their results indicate that microglia promote the growth of OPG and therefore suggest that the development of strategies targeting stromal cells such as microglia might be pursued