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Epigenetic modulation offers an alternative approach, as DNA methyltransferase and histone deacetylase inhibitors can derepress silenced CXCL9 and CXCL10 genes in tumor cells, thereby increasing effector T-cell infiltration [205]

Glossary 2OG, 2-oxoglutarate

Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions

Two neurotrophic factor gene therapies delivered via AAV2 vectors have provided either neurturin (AAV2-NRTN) or glial cell-line derived neurotrophic factor (AAV2-GDNF) to PD patients

However, it is important to note that DMF may exert opposite effects in different tissues depending on the dose

Immediately prior to endscopy and after drug treatment, venous blood samples were collected after 10-12 overnight fast and kept frozen after separation into plasma and erythrocyte fractions awaiting analysis