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ROS play a central role both upstream and downstream of the NF-B and TNF- pathways, which are the main mediators of the inflammatory response
Blood 110 , 401408 (2007)
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Dull needles cause more tissue damage and increase the likelihood of bruising or discomfort at the injection site
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Numerous animal studies using high-altitude or low-oxygen models have demonstrated reduced sperm concentration and motility, increased proportions of abnormally shaped sperm, and higher rates of sperm DNA fragmentation compared with normoxic controls
