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Clin Rheumatol 40:47134724

Diagnosis and treatment usually begin after the disease shows motor symptoms

doi: 10.1016/j.jconrel.2006.04.015

Stapp Car Crash J

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

Over time, membrane deformability declines due to changes in lipid content and oxidative damage to proteins (61, 62)
