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Description
Freezing compounded tirzepatide irreversibly damages the peptide structure
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Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes-2024
A significant change in pH affects the structure of all macromolecules, for instance, presence of a higher proportion of H + or low pH solution cleaves DNA double helix strands by protonating the DNA phosphodiester groups and consequently destabilizing the hydrogen bonds linking DNA nitrogenous bases guanine and cytosine (G-C) (Sorokin et al., 1986)
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