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Pharmacol Res 32:383389 [DOI] [PubMed] [Google Scholar] 146.Virmani MA, Caso V, Spadoni A, Rossi S, Russo F, Gaetani F (2001) The action of acetyl-l-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones

To avoid these issues, we maintained the temperature below 34C, which is a necessary compromise applied to all our cellular experiments

Factors influencing the time frame of results

The t test assured that the found results and the labeled content had no significant difference ( P = 0.95)

Lipid detection with LCMS The extracted lipids were separated using an ACQUITY UPLC BEH-C18 (2.1 100 mm, 1.7 m, Waters, Milford MA, USA) on a Vanquish Flex system (Thermo Fisher Scientific, MA, USA) and emitted into a Q-Exative mass spectrometer (Thermo Fisher Scientific)

Therefore, for patients with NAFLD, especially those with a restricted diet (e.g., meat) [42], it is safe to supplement with L-carnitine