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Hydroxocobalamin also appears to have a better safety profile in the setting of cyanide poisoning in conjunction with smoke inhalation

doi: 10.1016/j.phymed.2018.12.008 114 HeHQLawBYKZhangNQiuCLQuYQWuAGet al

Observations are dependent on concentration, exposure duration, and study design

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Clinical Trial Evidence & Failure The definitive human evidence for AOD-9604 comes from a Phase 2b double-blind, placebo-controlled trial published by Stier et al

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