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In 2023, Lopez-Otin proposed twelve markers of aging, including genomic instability, telomere loss, epigenetic changes, loss of protein balance, failure of macroautophagy, dysregulated nutrient sensing, mitochondrial dysfunction, cell senescence, stem cell depletion, altered intercellular communication, chronic inflammation, and dysbiosis

doi: 10.1016/j.ghir.2009.03.001 123 FalutzJPotvinDMamputuJCAssaadHZoltowskaMMichaudSEet al

Each box contains 10 vials, providing a convenient multi-session solution for clients who want consistent and visible results

While not directly indicative of release dynamics, these data offer valuable insights into the total levels of neurotransmitters available for release

Ouwendijk et al., 2021)