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For example, seaweed-derived components can modulate gut microbiota by altering the Firmicutes/Bacteroidetes ratio and increasing the abundance of beneficial bacteria like Bacteroides and Lactobacillus 44,45

British Journal of Pharmacology, 130, 851856

Frangieh, C

Recent research has shown that exercise can have a positive effect on the gut microbiota [151]

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Pathogenesis of Tissue Deposition of Urate Crystals Into Tophi Besides tissue supersaturation with urate and the effects of decreased temperature and decreased tissue pH to promote decreased urate solubility, other factors promote the transformation of soluble urate into urate crystals deposited in tophi ( Figure 1 - 6 )