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Mechanistically, CDK4/6 inhibitors regulate PD-L1 degradation via modulation of the CDK4SPOPE3 ligase axis
Various models are used to study PD, including -synuclein-mutant mice, the toxin MPTP, striatal injection of the catecholamine neurotoxin 6-hydroxydopamine (6-OHDA), and others (115)
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Bannister SC, Smith CA, Roeszler KN, Doran TJ, Sinclair AH, Tizard MLV
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