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Although NAC is promising as a supplement to both boost glutathione levels and potentially mitigate some of the issues related to oxidative stress [57,58], the research is not conclusive [59,60,61,62], and some of the findings are disease specific

Therefore, a comprehensive evaluation of safety and efficacy is essential during drug development

doi: 10.1146/annurev.arplant.50.1.601 6 BabyJ.JiniD
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doi: 10.1016/j.cellin.2025.100257 90 SunKLiCLiaoSYaoXOuyangYLiuYet al

Citric Acid Cycle FAD is reduced to FADH 2 in the citric acid cycle when succinate is converted to fumarate by succinic dehydrogenase as circled below
