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[DOI] [PubMed] [Google Scholar] 143.Veldt BJ, Heathcote EJ, Wedemeyer H, Reichen J, Hofmann WP, Zeuzem S, et al

The mechanism is aggregation: shear forces cause hydrophobic amino acid residues normally buried inside the peptide structure to flip outward, where they bind to hydrophobic regions on adjacent peptide molecules

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